Design and Prototype Construction of a Microneedle Drug Delivery Apparatus

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dc.contributor.authorPapadimitriou, Petrosel
dc.date.accessioned2022-11-01T07:57:21Z
dc.date.available2022-11-01T07:57:21Z
dc.date.issued2022-11-01
dc.identifier.urihttps://repository.ihu.edu.gr//xmlui/handle/11544/30109
dc.rightsDefault License
dc.subjectdrug deliveryen
dc.subjecthollow microneedleen
dc.subjectconceptual designen
dc.subject3d printingen
dc.subjectFDMen
dc.subjectDLPen
dc.titleDesign and Prototype Construction of a Microneedle Drug Delivery Apparatusen
heal.abstractThis dissertation deals with the design and prototype construction of a microneedle drug delivery apparatus. The purpose of the study is to design and offer a sustainable mechanism that can be manufactured, assembled, and utilized as easily and quickly as possible, minimizing the time and expense of the supply chain. This apparatus must become a realistic alternative method of providing a vaccine or drug in harsh circumstances, including humanitarian disasters or a lack of medical and nursing staff, something that is frequently observed in undeveloped countries. Simultaneously, with the use of microneedles, to be able to alleviate pain in the patient/user, who can benefit from the numerous advantages offered by them during administration. To carry out the task, it was necessary to first study the theoretical background for the various types of microneedles as well as the manufacturing techniques used. The mechanism under investigation involves the use of "Hollow Microneedles," which are internally perforated and are capable of delivering greater quantities of the active substance to the organism. The study for the development of this apparatus was conducted based on the state of the art of devices already built with the use of this type of microneedles, the function requirements, and finally, the technological and construction possibilities that we had. In terms of development, initially, designs of several concepts-ideas were created, that could be used to develop the desired application. After comparing the methods and possible alternatives, we were led to a final prototype which was designed with the appropriate details. The construction method which was chosen and applied was Additive Manufacturing, where the appropriate design proposals for the method were applied. The device was then built using a combination of custom-designed parts and conventional components such as screws in order to proceed to the last stage of experiments.en
heal.academicPublisherSchool of Science and Technology, Master of Science in Strategic Product Designen
heal.academicPublisherIDihuen_US
heal.accessfreeen_US
heal.advisorNameTzetzis, Dimitriosel
heal.bibliographicCitationPapadimitriou, Petros G., "Design and Prototype Construction of a Microneedle Drug Delivery Apparatus", School of Science and Technology, Master of Science in Strategic Product Design, International Hellenic University, 2022.en
heal.committeeMemberNameKaralekas, Dimitriosen
heal.committeeMemberNameTsongas, Konstantinosel
heal.dateAvailable2022-10-24
heal.languageenen_US
heal.licensehttp://creativecommons.org/licenses/by-nc/4.0en_US
heal.numberOfPages63en_US
heal.publicationDate2022-02
heal.recordProviderSchool of Economics, Business Administration and Legal Studies, MSc in Strategic Product Designen_US
heal.typemasterThesisen_US

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