Methodologies for 3D printing of Human neuronal cells
Φόρτωση...
Ημερομηνία
2024-04-15
Συγγραφείς
Tzitzo, Tzouliana
Τίτλος Εφημερίδας
Περιοδικό ISSN
Τίτλος τόμου
Εκδότης
Δικαιώματα
Default License
Άδειες
Παραπομπή
Παραπομπή
Περίληψη
Περίληψη
The rapid evolution of 3D printing technology stands at the forefront of innovation in
tissue engineering and regenerative medicine. This review outlines a comprehensive
investigation into methodologies for the 3D printing of human neuronal cells, a pursuit
that synergizes with the transformative capabilities of bioprinting technology.
Bioprinting, and its potential to fabricate scaffolds, cells, tissues, and organs with
reproducibility and high accuracy, serves as a pivotal element in advancing the
frontiers of neuroregenerative therapies.
Bioprinting technologies offer unique advantages and face distinct limitations. This
review integrates fundamental principles and key aspects of frequently used
bioprinting technologies, emphasizing recent advances in three-dimensional printing
applications. As we delve into the intricacies of biomaterial selection, bioink
formulation, and cutting-edge printing techniques within the context of neuronal
cells, the review underscores the critical role of biocompatibility, cell viability, and the
cellular microenvironment in influencing the printed product.
The overarching objective of this research is to optimize the 3D printing process for
human neuronal cells, aiming to enhance their viability, functionality, and
organizational precision. By exploring diverse approaches, this study aspires to unlock
the full potential of 3D printing, facilitating the creation of intricate neuronal
architectures.
The integration of 3D-printed neuronal cells into these diverse applications holds
immense promise for revolutionizing the treatment landscape of neurodegenerative
disorders. Through this comprehensive exploration of methodologies, recent
advances, challenges, and future directions, this review aims to contribute to the
scientific understanding of 3D-printed neuronal constructs, setting the stage for
transformative advancements in the field of neuroregenerative medicine.
Περιγραφή
Λέξεις-κλειδιά
3D, Bioprinting, Bioinks, Human neuronal cells, Organoids, Tissue engineering, Stem cells, Eurodegenerative diseases